主任

宋大千 教授、中心主任

现任吉林省光谱分析仪器工程技术研究中心主任,吉林省智能检测技术与仪器工程研究中心主任(兼)。入选国家“万人计划”科技创新领军人才、科技部“创新人才推进计划”中青年科技创新领军人才、教育部新世纪优秀人才、吉林省“长白山学者”特聘教授、吉林省第五批拔尖创新人才第二层次、吉林省高校首批“学科领军教授”、吉林省第十二批有突出贡献的中青年专业技术人才、吉林省教育厅新世纪科学技术优秀人才、长春市第五批有突出贡献专家。主持国家自然科学基金委仪器专项重点项目、面上项目、国家科技部“十一五”、 “十二五”科技支撑计划项目、国家重大科学仪器专项和省部级科研项目20余项;在国内外刊物上发表学术论文250余篇;获国家科技进步二等奖1项,吉林省科技进步一等奖3项、二等奖1项,中国分析测试协会CAIA奖一等奖1项,吉林省青年科技奖1项。获授权发明专利15项;制修订国家标准1项、行业和地方标准9项。

教育经历:

1994.09-1998.06 吉林大学化学系基地班 本科生

1998.09-2003.06 吉林大学化学系(学院)分析化学专业 硕博连读

工作经历:

2003.07-2004.12 吉林大学化学学院分析化学系 讲师

2005.01-2008.09 吉林大学化学学院分析化学系 副教授

2008.10-至今 吉林大学化学学院分析化学系 教授

2008.12-至今 吉林大学化学学院分析化学系 博士生导师

学术兼职与社会服务:

《高等学校化学学报》和《Chemical Research in Chinese Universities》杂志 编委

中国化学会高级会员

中国分析测试协会青年学术委员会 顾问委员

吉林省检测技术学会 副理事长

吉林省分析测试技术学会 常务理事

吉林省化学会 理事

研究成果:

1. 2023年,吉林省科技进步一等奖,《食用农产品质量安全快速检测关键技术与装备及其应用》,第一完成人

2. 2018年,吉林省科技进步一等奖,《饮水和空气安全快速检测关键技术及应用》,第一完成人

3. 2017年,国家科技进步二等奖, 《食品和饮水安全快速检测、评估和控制技术创新及应用》,第四完成人

4. 2016年,中国分析测试协会CAIA奖一等奖,《食品和饮用水中典型有害因子快速检测技术研究及应用》,第三完成人

5. 2014年,吉林省青年科技奖

6. 2012年,吉林省科技进步一等奖,《食品中掺假物和有益有害成分的检测》,第一完成人

7. 2009年,吉林省科技进步二等奖,《波长检测型表面等离子体子共振分析仪的研制及其应用》,第一完成人

代表论文:

[1] Ye Xiwen, Li Jingkang, Gao Dejiang, Ma Pinyi*, Wu Qiong*, Song Daqian*. A Dual-Mode Fluorescent Nanoprobe for the Detection and Visual Screening of Pathogenic Bacterial Spores. Analytical Chemistry, 2024, 96 (15), 6012-6020.

[2] Zhang Siqi, Ma Mo, Li Jingkang, Li Jiaxin, Xu Lanlan, Gao Dejiang, Ma Pinyi*, Han Hui*, Song Daqian*. A Pyroglutamate Aminopeptidase 1 Responsive Fluorescence Imaging Probe for Real-Time Rapid Differentiation between Thyroiditis and Thyroid Cancer. Analytical Chemistry, 2024, 96 (15), 5897-5905.

[3] Ye Zhuoxin, Ma Mo, Chen Yuxuan, Liu Ruiyan, Zhang Yan, Ma Pinyi*, Song Daqian*. Dual-microRNA-Controlled Electrochemiluminescence Biosensor for Breast Cancer Diagnosis and Supplemental Identification of Breast Cancer Metastasis. Analytical Chemistry, 2024, 96 (8), 3636-3644.

[4] Xu Lanlan, Ma Mo, Li Jingkang, Dai Dianfeng, Gao Dejiang, Ma Pinyi*, Wu Qiong*, Song Daqian*. Exploration of aminopeptidase N as new biomarker for early diagnosis of thyroid cancer. Biosensors and Bioelectronics, 2024, 244, 115808.

[5] Yang Jukun, Ma Mo, Wang Ningfei, Liu Lin, Zhao Chen, Li Jingkang, Chen Yuxuan, Ma Pinyi*, Song Daqian*. Spindle Monitor: A Tool for Real-Time Assessment and Concurrent Treatment of Postoperative Tumor Prognosis. Analytical Chemistry, 2023, 95 (48), 17654-17661.

[6] Xu Lanlan, Ma Mo, Li Jingkang, Gao Dejiang, Ma Pinyi*, Zhang Fangmei*, Song Daqian*. Leucine Aminopeptidase-Mediated Multifunctional Molecular Imaging Tool for Diagnosis, Drug Evaluation, and Surgical Guidance of Liver-Related Diseases. Analytical Chemistry, 2023, 95 (32), 12089-12096.

[7] Ye Xiwen, Gao Dejiang, Mu Xiaowei, Wu Qiong, Ma Pinyi*, Song Daqian*. Dual-Signal Triple-Mode Optical Sensing Platform for Assisting in the Diagnosis of Kidney Disorders. Analytical Chemistry, 2023, 95 (10), 4653–4661.

[8] Wang Wei, Li Jingkang, Liu Yibing, Zhang Wei, Sun Ying, Ma Pinyi*, Song Daqian*. A Strategy for the Determination of Alkaline Phosphatase Based on the Self-Triggered Degradation of Metal-Organic Frameworks by Phosphate. Analytical Chemistry, 2023, 95 (6), 3414-3422.

[9] Xu Lanlan, Chu Hongyu, Gao Dejiang, Wu Qiong, Sun Ying, Wang Zhenxin, Ma Pinyi*, Song Daqian*. Chemosensor with Ultra-High Fluorescence Enhancement for Assisting in Diagnosis and Resection of Ovarian Cancer. Analytical Chemistry, 2023, 95 (5), 2949-2957.

[10] Ye Zhuoxin, Liu Yibing, Pan Meichen, Tao Xiuli, Chen Yuxuan, Ma Pinyi*, Zhuo Ying*, Song Daqian*. AgInZnS Quantum Dots as Anodic Emitters with Strong and Stable Electrochemiluminescence for Biosensing Application. Biosensors and Bioelectronics, 2023, 228, 115219.

[11] Ma Mo, Dai Dianfeng, Ma Pinyi*, Wu Qiong, Gao Dejiang, Song Daqian*. Biocompatible ratiometric fluorescent chemosensor for ultrasensitive detection of endogenous aminopeptidase N In Vitro and In Vivo. Sensors and Actuators B: Chemical, 2023, 379, 133228.

[12] Li Jiaxin, Cao Jingrui, Wu Wen, Xu Lanlan, Zhang Siqi, Ma Pinyi*, Wu Qiong*, Song Daqian*. A molecular imaging tool for monitoring carboxylesterase 2 during early diagnosis of liver-related diseases. Sensors and Actuators B: Chemical, 2023, 377, 133122.

[13] Zhao Lihe, Chu Hongyu, Zhang Siqi, Xu Lanlan, Yang Bin, Ma Pinyi*, Wu Qiong*, Song Daqian*. A novel probe for identifying breast cancer cells based on fluorescence response of the cascade process of biothiol and viscosity. Sensors and Actuators B: Chemical, 2023, 375, 132883.

[14] Liu Lin, Chu Hongyu, Yang Jukun, Sun Ying, Ma Pinyi*, Song Daqian*. Construction of a magnetic-fluorescent-plasmonic nanosensor for the determination of MMP-2 activity based on SERS-fluorescence dual-mode signals. Biosensors and Bioelectronics 2022, 212, 114389.

[15] Mu Xiaowei, Liu Xin, Ye Xiwen, Zhang Wei, Li Lu*, Ma Pinyi*, Song Daqian*. Branched poly(ethylenimine) carbon dots-MnO2 nanosheets based fluorescent sensory system for sensing of malachite green in fish samples. Food Chemistry 2022, 394, 133517.

[16] Liu Lin, Zhang Hua*, Wang Zenxin, Song Daqian*. Peptide-functionalized upconversion nanoparticles-based FRET sensing platform for Caspase-9 activity detection in vitro and in vivo. Biosensors and Bioelectronics 2019, 141, 111403. 

[17] Wu Qiong, Sun Ying, Zhang Di, Li Shuo, Zhang Yue, Ma Pinyi, Yu Yang, Wang Xinghua, Song Daqian*. Ultrasensitive magnetic field-assisted surface plasmon resonance immunoassay for human cardiac troponin I. Biosensors and Bioelectronics 2017, 96, 288-293. 

[18] Wu Qiong, Sun Ying, Zhang Di, Li Shuo, Wang Xinghua, Song Daqian*. Magnetic field-assisted SPR biosensor based on carboxyl-functionalized graphene oxide sensing film and Fe3O4-hollow gold nanohybrids probe. Biosensors and Bioelectronics 2016, 86, 95-101. 

[19] Zhang Jia, Sun Ying, Xu Bo, Zhang Hua, Gao Yan, Zhang Hanqi, Song Daqian*. A novel surface plasmon resonance biosensor based on graphene oxide decorated with gold nanorod–antibody conjugates for determination of transferrin. Biosensors and Bioelectronics 2013, 45, 230-236. 

[20] Zhang Hua, Sun Ying, Gao Shang, Zhang Jia, Zhang Hanqi, Song Daqian*. A Novel Graphene Oxide-Based Surface Plasmon Resonance Biosensor for Immunoassay. Small 2013, 9 (15), 2537-2540.